DFG Project
Understanding and predicting nanopore transport by polymer chain composition design for ionic circuits
The proposed project aims to generate optimized nanopore design strategies for technological nanopore-based ionic circuits in future autonomous sensing.
To achieve this goal, the project will interdigitate new experimental nanopore functionalization strategies in collaboration with the latest developments in molecular theory on transport through polymer functionalized nanopores to resolve, understand, predict, and experimentally control all relevant processes and their interplay within a nanopore including polymer conformational changes, charge distribution, charge regulation, polarity, and ligand binding as well as ion distribution within a nanopore. The insights gained from a strong coupling of nanopore functionalization and molecular modeling will enable us to define design criteria for selective, directed transport with concentration-time profile control, an essential tool for technological nanopore-based ionic circuits.
Involved team members: M. Zoppelt
Collaboration: Prof. Igal Szleifer, Northwestern University, US
Funding: DFG